Approaching a decades-old goal: Making blood stem cells from patients’ own cells

Researchers at Boston Children’s Hospital have, for the first time, generated blood-forming stem cells in the lab using pluripotent stem cells, which can make virtually every cell type in the body. The advance, published in the journal Nature, opens new avenues for research into the root causes of blood diseases and to creating immune-matched blood cells for treatment purposes, derived from patients’ own cells. “We’re tantalizingly close to generating bona fide human blood stem cells in a dish,” says senior investigator George Daley, MD, PhD, who heads a research lab in Boston Children’s Hospital’s Stem Cell Program and is dean…
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