What does it take for an AIDS virus to infect a person?

Upon sexual exposure, the AIDS virus must overcome some mighty barriers to find the right target cell and establish a new infection. It must traverse the genital mucosa and squeeze through tightly packed epithelial cells meant to keep invaders out. And then it must thwart the initial immune-system alarm bell in the form of type 1 interferons. In fact, according to some studies, only about 1 in 1,000 unprotected sexual exposures lead to a successful HIV-1 infection. “What is unique about these transmitted viruses that make it this far?” asked Beatrice Hahn, MD, a professor of Medicine and Microbiology in…
View More/Source Article